The "Native" Difference: Why Structure Matters for Efficacy
If you’ve spent time in the lab, you know that protein function is dictated by its shape. Most collagen on the market is denatured by heat or chemicals to create peptides. However, for Undenatured Collagen Type II, the goal is the exact opposite.
Key Structural & Functional Advantages of Native Collagen Type II
The native structure of our Undenatured Collagen Type II delivers unique biological benefits that denatured alternatives cannot match:
Preserving the Triple Helix
The active site of Type II collagen is its three-dimensional triple-helix structure. When this structure remains "native" (undenatured), it contains specific epitopes—biological markers that the immune system recognizes.
The Mechanism of Oral Tolerance
Our undenatured collagen works through a process called Oral Tolerance. When ingested in its native form, it reaches the Peyer’s patches in the small intestine. Here, it "trains" the immune system to stop attacking the body's own articular cartilage. This immune-modulation helps reduce inflammation and supports the body’s natural repair processes, often more effectively than much larger doses of glucosamine or chondroitin.
